Einstein International Journal Organization(EIJO)

Abstract

It is a common precaution to stop antiplatelet drugs prior to the extraction procedures. In the present study we have analyzed the post extraction bleeding of those patients who were under single antiplatelet medication (Group 1: Aspirin, Group 2: Clopidogrel) with that of control group (Group 3) in our institute. All the patients were given a brief description of the procedure and a medical fitness from those taking antiplatelet were taken from the consulting physician before the procedure. All the measures to control the post-extraction bleeding were assembled before the procedure. All patients who received antiplatelet were carefully examined to assess the post extraction bleeding and were compared with that of control group.

1. Atanaska S. Dinkova, Dimitar T. Atanaso, Ludmila G. Vladimirova-Kitova.Discontinuation of Oral Antiplatelet Agents before Dental Extraction - Necessity or Myth? :Folia Medica 2017;59(3):336-34
2. Yokoyama T, Yamasaki F, Yamashita K, Manabe M, Suwa K,.Bleeding time prolonged by daily low dose aspirin is  shortened by one medium dose aspirin. Acta Anesthesiologica Scandinavica 52, 1126-1130.
3. Wahl MJ. Dental surgery and antiplatelet agents: bleed or die. Am J Med 2014;127(4):260-7.
4. Anti-Platelet Trialists’ Collaboration, “Collaborative overview of randomized trials of antiplatelet therapy: prevention of death, myocardial infarction, and stroke by prolonged antiplatelet therapy in various categories of patients,” British Medical Journal, vol. 308, no. 6921, pp. 81–106, 1994.
5. Antithrombotic Trialists’ Collaboration, “Collaborative metaanalysis of randomised trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high risk patients,” British Medical Journal, vol. 324, no. 7329, pp. 71–86, 2002.
6. J. E. Dalen, “Aspirin to prevent heart attack and stroke: what’s the right dose?” American Journal of Medicine, vol. 119, no. 3, pp. 198–202, 2006.
7. C. D. Owens and M. Belkin, “Thrombosis and coagulation: operative management of the anticoagulated patient,” Surgical Clinics of North America, vol. 85, no. 6, pp. 1179–1189, 2005.
8. W. Burger, J.-M. Chemnitius, G. D. Kneissl, and G. Rucker, ¨ “Low-close aspirin for secondary cardiovascular prevention— cardiovascular risks after its perioperative withdrawal versus bleeding risks with its continuation—review and metaanalysis,”  Journal of Internal Medicine, vol. 257, no. 5, pp. 399– 414, 2005.
9. N. G. Daniel, J. Goulet, M. Bergeron, R. Paquin, and P.-E. Landry, “Antiplatelet drugs : is there a surgical risk?” Journal of the Canadian Dental Association, vol. 68, no. 11, pp. 683–687, 2002.
10. S. T. Sonis, R. C. Fazio, L. Fang et al., PrincIplos e Pratica de Medicina Oral, Guanabara Koogan, Rio de Janeiro, Brazil, 2nd edition, 1996.
11. M. J. Wahl, “Myths of dental surgery in patients receiving anticoagulant therapy,” The Journal of the American Dental Association, vol. 131, no. 1, pp. 77–81, 2000.
12. A. Canigral, F.-J. Silvestre, G. Ca ˜ nigral, M. Al ˜ os, A. Garcia- ´ Herraiz, and A. Plaza, “Evaluation of bleeding risk and measurement methods in dental patients,” Medicina Oral, Patologia Oral y Cirugia Bucal, vol. 15, no. 6, pp. e863–e868, 2010.
13. J. D. Nielsen, C. A. Lætgaard, S. Schou, and S. S. Jensen, “Minor dentoalveolar surgery in patients ungergoing antithrombotic therapy,” Ugeskrift for Laeger, vol. 171, no. 17, pp. 1407–1409, 2009.
14. R. H. Allard, J. A. Baart, P. C. Huijgens, and J. P. van Merkesteijn, “Antithrombotic therapy and dental surgery with bleeding,” Nederlands Tijdschrift voor Tandheelkunde, vol. 111, no. 12, pp. 482–485, 2004.
15. T. Lillis, A. Ziakas, K. Koskinas, A. Tsirlis, and G. Giannoglou, “Safety of dental extractions during uninterrupted single or dual antiplatelet treatment,” American Journal of Cardiology, vol. 108, no. 7, pp. 964–967, 2011.
16. M. E. Bertrand, “When and how to discontinue antiplatelet therapy,” European Heart Journal Supplements, vol. 10, pp. A35– A41, 2008.