An International Journal House

Einstein International Journal Organization(EIJO)

Connecting People With Genius Thought

Einstein International Journal Organization(EIJO) is an international Genius Thought journals platform .
JOURNALS || EIJO Journal of Science, Technology and Innovative Research (EIJO – JSTIR) [ ISSN : 2455 - 9938 ]
Comparative evaluation of tetracycline fibers (periodontal plus abtm) and chlorhexidine chip (periocol-cgTM) as an adjunct to scaling and root planing in the treatment of chronic periodontitis - A split mouth study

Author Names : 1Dr. Vidushi Narang, 2Dr. Deepak Grover,3Dr. Navneet Kaur, 4Dr. Gurpreet Kaur  Volume 6 Issue 6
Article Overview

Background:  The most important goal of periodontal therapy is to reduce or eliminate the subgingival micro-organisms associated with periodontal disease and to maintain periodontal health. Scaling and root planing is the traditional method and has shown effective treatment for chronic periodontitis but it does not necessarily eliminate all the pathogens. Hence, the need for antimicrobial therapy as local drug delivery agents was felt. The objective of the study was to compare and evaluate the effectiveness of Tetracycline fibers (Periodontal Plus ABTM) and Chlorhexidine chip (Periocol – CGTM) as an adjunct to scaling and root planing in the management of chronic periodontitis.

Materials and Methods: 5 patients, with chronic periodontitis were selected and randomly divided into 3 groups/sites Group 1- subjects were treated with scaling and root planing alone (SRP), Group 2 - subjects were treated tetracycline fibers as an adjunct to SRP and Group 3 - subjects were treated with chlorhexidine chip as an adjunct to SRP. Clinical parameters included probing pocket depth, relative attachment level, plaque index, gingival index recorded at baseline, Imonth and 3months.

Results: All the groups showed significant improvement in probing pocket depth and relative attachment level gain at different time intervals of 1 month and 3 months when treated with chlorhexidine chip, tetracycline fibers and scaling and root planing alone. However, the best results were obtained in the group which received Chlorhexidine chip as an adjunct to scaling and root planing.

Conclusion: It can be concluded that the use of chlorhexidine chip (Periochip) as an adjunct to Scaling and root planing was safe and provides a significant reduction in Plaque Index score and Gingival Index score.

Keywords: Tetracycline fibers; Chlorhexidine chip; Chronic periodontitis; Scaling and root planing; Local drug delivery.

Reference
  1. Haffajee AD, Cugini MA, Dibart S, Smith c, Kent RL, Socransky SS. The effect of SRP on the clinical and microbiological parameters of periodontal diseases. Journal of Clinical Periodontology 1997;24(5):324-334.
  2. Cobb CM. Microbes, Inflammation, Scaling and Root Planing, and the Periodontal Condition. The Journal of Dental Hygiene. 2008;82(2):4-9.
  3. Heasman P, Heasman L, Stacey F, McCracken G. Local delivery of chlorhexidine gluconate (PerioChipTM) in periodontal maintenance patients. Journal of Clinical Periodontology. 2001;28(1):90-95.
  4. Sharma NK, Prasad, A. Evaluation of Efficacy of Tetracycline as a Local Drug Delivery System in the Treatment of Chronic Periodontitis as an Adjunct to Scaling and Root Planing – A Clinical and Microbiological Study. International Journal of Contemporary Medical Research. 2017; 4(5):998-1003.
  5. Ma L, Diao, X. Effect of chlorhexidine chip as an adjunct in non-surgical management of periodontal pockets: a meta-analysis. BMC Oral Health. 2020; 20(262):1-14.
  6. Qyirynen M, Zhao H, Soers C, Dekeyser C, Pauwels M, Coucke W et al. A 0.05% cetyl pyridinium chloride/0.05% chlorhexidine mouth rinse during maintenance phase after initial periodontal therapy. Journal of Clinical Periodontology. 2000;32 (4):390-400.
  7. Greenstein G, Tonetti M. The Role of Controlled Drug Delivery for Periodontitis. Journal of Periodontology. 2000; 71(1):125-140.
  8. Goodson JM. Pharmacokinetic principles controlling efficacy of oral cavity. Journal of Dental Research. 1989;68:1625-32.
  9. Minabe M, Takeuchi K, Tamura T, Hori T, Umemoto T. Subgingival administration of tetracycline on a collagen film. Journal of Periodontology. 1989; 60:552-6.
  10. Gupta R, Pandit N, Aggarwal S, Verma A. Comparative evaluation of subgingivally delivered 10% doxycyclate hyclate and xanthan-based chlorhexidine gels in the treatment of chronic periodontitis. Journal of Contemporary Dental Practice. 2008; 9(7):25-32.
  11. Paolantonio M, D’Ercole S, Pilloni A, D’Archivio D, Lisanti L, Graziani F et al. Clinical, microbiologic and biochemical effects of subgingival administration of a xanthan-based chlorhexidine gel in the treatment of periodontitis: a randomized multicentrer trial. Journal of Periodontology. 2009;80(9):1479-92.
  12. Mizrak T, Guncu GN, Caglayn F, Balci TA, Aktar GS, Ipek F. Effect of controlled release chlorhexidine chip on clinical and microbiological parameters and prostaglandin E2 levels in gingival crevicular fluids. Journal of Periodontology.2006; 77(3):437-443.
  13. Stabholz A, Sela MN, Friedman M, Golomb G, Soskolne A. Clinical and microbiological effects of sustained release chlorhexidine in periodontal pocket. Journal of Clinical Periodontology. 1986;13(8):783-788.
  14. Rodrigues IFG, Machion L, Casati MZ, Nociti FH, Toledo SD, Sallum AW et al . Clinical evaluation of the use of locally delivered chlorhexidine in periodontal maintenance therapy. Journal of Periodontology. 2007;78(4):624-626.
  15. Soskolne WA, Chajek T, Flashner M, Landau I, Stabholz A, Kolatch B et al . An in vivo study of the chlorhexidine release profile of the PeriochipTM in the gingival crevicular fluid, plasma and urine. Journal of Clinical Periodontology. 1998;25(12):1017-1021.
  16. Jeffcoat MK, Palcains KG, Weatherford TW, Reese M, Geurs NC. Use of a biodegradable chlorhexidine chip in the treatment of adult periodontitis: Clinical and radiographic findings. Journal of Periodontology. 2000;71(2):256-262.
  17. Azmak N, Atilla G, Luoto H, Sorsa T. The effect of subgingival controlled- release delivery of chlorhexidine chip on clinical parameters and matrix metalloproteinases – 8 levels in gingival crevicular fluid. Journal of Periodontology. 2002; 73(6):608-615.
  18. Paolantonio M, Angelo MD, Grassi RF, Perinetti G, Piccolomini R, Pizzo G et al. Clinical and microbiologic effects of subgingival controlled – release delivery of chlorhexidine chip in the treatment of periodontitis: A multicentre study. Journal of Periodontology. 2008;79(2): 271-282.
  19. Morrison EC, Ramjford SP, Hill RW. Short-term effects of initial, nonsurgical periodontal treatment (hygienic phase). Journal of Clinical Periodontology. 1980;6:352-357.