Einstein International Journal Organization(EIJO)

Abstract

Carissa carandas Linn. (Karaunda) is a traditional medicinal plant widely hired in Ayurveda, Unani, and oldsters remedy for its healing houses. The present take a look at aimed to research the phytochemical composition, antioxidant, and antimicrobial functionality of ethanolic leaf extracts of C. Carandas. Ethanolic extracts had been prepared through maceration and subjected to initial phytochemical screening, which confirmed the presence of alkaloids, flavonoids, tannins, saponins, phenols, glycosides, and steroids. Quantitative evaluation using GC–MS located out diverse phytoconstituents, such as phenolic compounds, flavonoids, and bioactive hydrocarbons. The antimicrobial hobby have become assessed with the aid of the Kirby–Bauer disc diffusion approach in opposition to bacterial traces (E. Coli, Staphylococcus aureus) and fungal lines (Candida albicans). The consequences indicated slight antifungal interest with powerful inhibition at 250 µg/disc, at the same time as antibacterial interest in the direction of S. Aureus have become obtrusive at higher concentrations, although negligible hobby changed into noted against E. Coli. The antioxidant interest determined with the aid of manner of the DPPH radical scavenging assay tested an IC50 price of 296.4 µg/mL for the plant extract compared to 3.70 µg/mL for ascorbic acid. Overall, the findings endorse that C. Carandas leaves comprise bioactive phytochemicals with mild antimicrobial and antioxidant ability, helping its ethnomedicinal applications and highlighting its scope for similarly pharmacological exploration.

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