Einstein International Journal Organization(EIJO)

Abstract

Now a day’s various diseases caused by growth of many pathogenic bacteria, fungi, viruses and other organisms. In the treatment of such diseases we commonly use many types of antibiotics. But there is an always threat of developing resistance to these antibiotics.  In last two decades scientist are failing to find out new or potent antibiotics. Hence it is essential to find herbal medicines which possess antimicrobial activity. Also we have to research on them by using new scientific methods to prove there efficacy on modern ground.

Hence in this study we have a research on activity of Sesbania grandiflora against Staphylococcus aureus, Streptococcus pyogenes, Salmonella typhi and Candida albicans. In this research we found that extract of Sesbania grandiflora shows strong inhibitory activity against Staphylococcus aureus. Extract does not show activity against Streptococcus pyogenes. Among the observed result the chloroform extract of Sesbania grandiflora shows greater antimicrobial activity than methanolic extract. It indicates that chloroform is more useful to make extract of Sesbania grandiflora. As far antimicrobial activity of S. grandiflora against Salmonella typhi is observed that it shows moderate activity but when it used with other antibiotics it shows strong synergistic effect against Salmonella typhi. It is also observed that crude extract of Sesbania grandiflora alone does not shows any activity against Candida albicans but when used with other Antifungal agent it shows improved antifungal activity. It indicates that extract of Sesbania grandiflora shows synergistic effect while acting against salmonella typhi and Candida albicans.

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